99% Purity Nootropics Powder Isrib (TRANS-ISOMER) CAS 1597403-47-8

• CAS No.: 1597403-47-8
• Formula: C22h24cl2n2o4
• EINECS: N/a
• Type: Peptides Powder
• Appearance: Powder
• Quality: Top Quality
• Model NO.: CAS 1597403-47-8
• Colour: White
• Mf: C22h24cl2n2o4
• MW: 1597403-47-8
• Packing: 1kg/Foil Bag or 25kgs/Drum
• Usage: for Research Use Only
• Transport Package: as Customer′s Requirement
• Specification: 1G/Foil bag
• Trademark: Redgia
• Origin: China

Product Description

99% Purity Nootropics Isrib (TRANS-ISOMER) CAS 1597403-47-8

Product name	Isrib
Appearance	White powder
Purity	99%
Storage	Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Shelf Life	24 Months

Description

Trans ISRIB (integrated stress response inhibitor) as a drug, imparts resistance to the cells against the
downstream effects of eukaryotic initiation factor 2 (eIF2)α phosphorylation such as activating transcription factor
4 (ATF4) and eukaryotic translation initiation factor 4E (eIF4E)-binding protein 1 (4E-BP1) induction.

Application&Function

Trans ISRIB is a blood- brain barrier penetrant, potent and selective inhibitor of integrated stress response (ISR)
that impairs adaptation to ER stress. Trans ISRIB is a potent inhibitor of PERK signaling, which potently reverses
the effects of eIF2a phosphorylation and restores the cells translation capacity. Trans ISRIB enhances cognitive
memory in rodents.

Trans ISRIB (integrated stress response inhibitor) has been used as an inhibitor of integrated stress response.