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  • Buy on Line High Quality Pharmaceutical Intermediates Ll-37 Raw Powder CAS 154947-66-7 Ll-37
  • Buy on Line High Quality Pharmaceutical Intermediates Ll-37 Raw Powder CAS 154947-66-7 Ll-37
  • Buy on Line High Quality Pharmaceutical Intermediates Ll-37 Raw Powder CAS 154947-66-7 Ll-37
  • Buy on Line High Quality Pharmaceutical Intermediates Ll-37 Raw Powder CAS 154947-66-7 Ll-37
  • Buy on Line High Quality Pharmaceutical Intermediates Ll-37 Raw Powder CAS 154947-66-7 Ll-37
  • Buy on Line High Quality Pharmaceutical Intermediates Ll-37 Raw Powder CAS 154947-66-7 Ll-37

Buy on Line High Quality Pharmaceutical Intermediates Ll-37 Raw Powder CAS 154947-66-7 Ll-37

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Basic Info.

Model NO.
CAS 154947-66-7
Colour
White
Name
Li-37
Mf
C205h340n60o53
MW
N/a
CAS
154947-66-7
Packing
1kg/Foil Bag or 25kgs/Drum
Usage
for Research Use Only
Transport Package
as Customer′s Requirement
Specification
1G/Foil bag
Trademark
Redgia
Origin
China

Product Description

Buy on Line High Quality Pharmaceutical Intermediates Ll-37  Raw Powder CAS 154947-66-7 Ll-37
Product name Ll-37
Appearance White powder
Purity 99%
Storage Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Shelf Life 24 Months


Description

The cathelicidin anti-microbial peptide LL-37 is involved in the reepithelialization of human skin wounds and is

lacking in chronic ulcer epithelium. LL-37(human) is a cathelicidin-derived peptide with antimicrobial and angiogenic

activity. Antimicrobial peptide derivative of human cathelicidin.

Antimicrobial peptide derivative of human cathelicidin. Induces FPRL1-mediated chemotaxis of human neutrophils,

monocytes and T cells in vitro. Promotes wound healing following skin-targeted electroporation of a plasmid encoding

hCAP-18/LL-37 in mice. Also triggers apoptosis in colon cancer cells. 



Application&Function

LL-37 is the only known human Cathelicidin is a big protein family where the members exhibit diverse functions.

These peptides, essentially produced by macrophages and polymorphonuclear leukocytes (both types of white blood

cells), have bactericidal action. They have been found to have shown other substantial effects as well. The entire group

is often referred to as antimicrobial peptides (AMPs). LL-37 in particular has been found to play significant roles in

autoimmune disease, cancer, and wound healing.


1.Reduce apoptotic death of keratinocytes.

2.Improve IFN-alpha synthesis.

3.Suppress signaling through toll-like receptor 4 (TLR4).

4.Modify chemotaxis of neutrophils and eosinophils.

5.Trigger IL-18 production, and reduce levels of atherosclerotic plaques.


 






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Registered Capital
500000 RMB
Management System Certification
ISO 9001, ISO 14000