High Grade Oligopeptide Pharmaceutical Ingredients 99% Decapeptide-12 Raw Powder CAS 137665-91-9 for Sensitive Skin Care

• CAS No.: 137665-91-9
• Formula: C65h90n18o17
• EINECS: N/a
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Refined
• Model NO.: CAS 137665-91-9
• Colour: White
• Mf: C65h90n18o17
• MW: 1395.52
• Transport Package: as Customer′s Requirement
• Specification: 10mg/vial or 1g/bottle
• Trademark: Redgia
• Origin: China

Product Description

High Grade Oligopeptide Pharmaceutical Ingredients 99% Decapeptide-12 Raw Powder CAS 137665-91-9 For Sensitive Skin Care

Product name	Decapeptide-12
Appearance	White powder
Purity	99%
Storage	Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
Shelf Life	24 Months

 

Description
 

Decapeptide-12 reversibly binds to tyrosinase, an enzyme found in a number of different pigment-producing cells.

It prevents tyrosinase from catalyzing the oxidation of phenols, the first step in melanin production. In mammals,

tyrosinase is found only in melanosomes, special compartments within pigment-producing cells.
 
Tyrosinase is not preserved across species and, in fact, can differ drastically in structure even among closely-related

species. In humans, differences in the efficiency of tyrosinase determine skin color and are the result of slight

modifications in the TYR gene found on chromosome 11 .

 Decapeptide-12 is approximately 17 times more potent than previous treatments for hyperpigmentation, including

hydroquinon/e . Studies in cultured melanocytes over 7 days demonstrated a 27%-43% reduction in melanin content .

Decapeptide-12 has undergone multiple animal trials and may eventually be included in commercial products for treating

hyperpigmentation.


Application&Function
 

Decapeptide-12 is a cosmetic raw material that inhibits melanin formation, lightens pigmentation, reduces

pigmentation,and evens and brightens skin tone. It was developed by researchers at Stanford Dermatology and

is the only one proven to effectively inhibit Tyrosinase (tyrosinase promotes excessive production of melanin,

resulting in uneven pigmentation,dark spots, etc.), a novel peptide activity. Decapeptide-12 is an oligopeptide that

is made up of just 12 amino acids. This oligopeptide is known for its anti-tyrosinase activity. Tyrosinase is found in

plant and animal tissues and is responsible for catalyzing melanin and other pigments. Decapeptide-12 is being

investigated for its possible ability to reduce skin darkening. It's able to interfere with tyrosinase and lighten skin

in animal models. Decapeptide-12 reduces the appearance of hyperpigmentation-age spots, sun spots, uneven

skin tone and photo damage-without the typical side effects of other brighteners like irritation and redness. Plus,

soothing antioxidants like licorice root also ease sensitive skin.